Paper Alert: BACE1 Required for Muscle Spindle, Motor Control
Scientists have discovered yet another function for β-secretase (BACE1), the enzyme that kick-starts amyloidogenic processing of the amyloid-β precursor protein...
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Scientists have discovered yet another function for β-secretase (BACE1), the enzyme that kick-starts amyloidogenic processing of the amyloid-β precursor protein...
Using hormone therapy early in menopause neither helps nor harms cognition, researchers report.
Magnetic resonance spectroscopy bolsters hypothesis that ALS results from too much glutamate and too little GABA
Growing evidence suggests that innate immune cells prevent or slow Alzheimer's disease by chewing up Aβ and promoting its clearance.
Meeting Explores Regulatory Requirements for Parkinson's MCI Michael J. Fox Foundation Conference
Similar to Alzheimer's disease, PD dementia begins with subtle deficits in cognition that progress to symptoms recognizable as mild cognitive impairment.
By looking for structural DNA variations in Alzheimer’s families, researchers identified 18 new genes that may play a role in AD pathology.
Eating fewer saturated fats and simple sugars reduces harmful forms of Aβ in the cerebrospinal fluid, scientists report.
In a series of eight reviews, titled "Focus on Neurotechniques," researchers describe how approaches such as optogenetics and stem cells are revolutionizing neuroscience.
The experimental drug NitroMemantine protects synapses from Aβ oligomer toxicity in mice by blocking extrasynaptic NMDA receptors.
Brain imaging distinguishes ALS patients with C9ORF72 expansions from those with other forms of the disease.
An ultra-high-resolution 3D map of the human brain promises to help scientists studying neuroanatomy, neurosurgery, neurodegenerative disease, and more.
Before cognition falters, Alzheimer’s disease wreaks havoc on synapses, the brain’s subcellular communication hubs.