A Diagnostic Test for Large Aβ Oligomers?
Researchers in Japan have developed an assay for amyloid-β (Aβ) oligomers that they suggest might be a useful diagnostic test for Alzheimer disease...
6397 RESULTS
Sort By:
Researchers in Japan have developed an assay for amyloid-β (Aβ) oligomers that they suggest might be a useful diagnostic test for Alzheimer disease...
The latest gene to join the amyotrophic lateral sclerosis canon is D-amino acid oxidase, an enzyme that protects motor neurons from excitotoxicity...
It was once <em>All About Eve</em>, but what about Adam, or ADAM10, to be more precise?...
Japanese scientists have now incorporated an unusual variant of amyloid precursor protein (APP) into a new mouse model...
Mounting scientific evidence continues to dash once-high hopes that lithium can help people with amyotrophic lateral sclerosis...
Many neurodegenerative diseases involve a common pattern of protein misfolding, aggregation, and toxicity...
An analysis provides evidence that caspase activation may precede tangle formation...
It is easy to confuse one motor neuron disease for another: amyotrophic lateral sclerosis, primary lateral sclerosis, and lower motor neuron disease can all mimic each other...
Advances in therapy saw little sprigs of news pop up in talks that otherwise took stock of the current status of immunotherapy as one of the major new approaches...
Following disappointing results in its Phase 3 CONNECTION trial of Dimebon for Alzheimer disease (AD), Medivation, Inc., is cutting its workforce...
Researchers have identified some potential drug targets; ARF’s regular readers may not be surprised that one of their strongest hits points to the immune system...
Last week, scientists from around the world gathered in the Swiss-French border city of Geneva...
Activation of muscarinic acetylcholine receptors is known to steer APP down the non-amyloidogenic, α-secretase pathway...
People worried about a family history of Alzheimer disease may want to consider which parent was affected...
A study last year concluded, astonishingly, that the brain’s resident phagocytes had no impact on growth or clearance of Aβ plaques in AD transgenic mice...