Bad Guys—Aβ Oligomers Live Up to Reputation in Human Studies
The finger pointing in the molecular culprit behind AD has shifted in recent years from amyloid plaques to its building blocks—free-floating Aβ peptides...
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The finger pointing in the molecular culprit behind AD has shifted in recent years from amyloid plaques to its building blocks—free-floating Aβ peptides...
Several recent studies have shown that memory formation, learning, and age-associated cognitive decline are linked to remodeling of chromatin proteins...
At present, at least four companies are developing amyloid imaging agents coupled to the radiotracer 18F rather than 11C...
At the 4th Human Amyloid Imaging Conference, the question kept cropping up of what is the right reference region to use in amyloid imaging...
Since the first major paper on human amyloid imaging appeared, a burgeoning field of research has sprung up...
As if blindness wasn’t enough, mutations in the gene for optineurin (OPTN), which can lead to glaucoma, also appear to cause amyotrophic lateral sclerosis...
A common gene variant that puts many people at risk for obesity may also make those who have it more vulnerable to developing Alzheimer disease...
Creating inhibitors for γ-secretase has felt a bit like trying to slay an unseen beast. That’s because this fearsome protein complex...
You might be inclined to wonder about your refuse collector if garbage was piling up in your neighborhood. What about in your brain?...
The Alzforum brings you a journalistic summary by reporter Pat McCaffrey enhanced by slide decks from the majority of presentations...
When is a kinase not a kinase? When it’s cyclin-dependent kinase 5 (Cdk5), perhaps...
A magnetic resonance imaging (MRI) study links reduced hippocampal volume and memory decline in older adults with lower serum levels of BDNF...
However far apart the worlds of television and scientific research may seem, they came together for a study published online in Nature...
Toronto: 6th Sense—GWAS Picks Up New AD Risk Variant Toronto: Mucke, Miller Share Prestigious Potamkin Prize Toronto: In Small Trial, IVIg Slows Brain Shrinkage American Academy of Neurology: 2010 Annual Meeting
There may be a new reason to support your local phlebotomist—if data from an extension trial of 24 people hold up in Phase 3, that is...