Honolulu: Intranasal Insulin Trial Claims Promise in MCI, AD
Intranasal insulin seemed to improve certain measures of cognition and daily function, as well as biomarker profiles, in patients with MCI or early AD...
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Intranasal insulin seemed to improve certain measures of cognition and daily function, as well as biomarker profiles, in patients with MCI or early AD...
For the first time, a paper details a molecular mechanism that links tau to Aβ toxicity at the synapse...
If β amyloid is indeed an early driver of Alzheimer disease pathogenesis, AD patients presumably churn out the peptide too quickly, clear it too slowly, or both...
The sirtuin protein SIRT1 is emerging as an important player in learning and memory...
AD diagnosis is moving from the bedside to the desktop, suggests Jason Karlawish...
Tomm40 has created a stir in AD research with the recent proposal that length of polymorphisms of this gene can help predict at what age a person may develop late-onset AD...
Maybe you can teach old dogs new tricks—and reduce their amyloid-β burden...
Two new papers show that vitamins may have potential as protectors for the brain...
Two new papers detail specific, discrete pathways of memory formation that share a common element, namely, signaling by CREB...
TDP-43 is intimately linked with ALS, but the mystery remains as to what the protein is normally meant to do, and what goes wrong when it mutates...
The protein reelin helps rein in pathology in Alzheimer disease mice, according to a recent report...
DIAN Dispatch From Hawaii: After Slow Start, Network Is Humming DIAN Dispatch from Hawaii: Glimpse at Data, Push for Trials The DIAN represents a bold attempt at pushing Alzheimer's clinical research squarely into the preclinical phase. It enrolls ad
Regulatory approval could be on the horizon for an amyloid tracer being developed for brain imaging using positron emission tomography (PET)...
Leaders of DIAN gathered to brief each other to present to some 30 pharmaceutical industry scientists the first cut of baseline data from this ongoing biomarker study...
After more than a year of rumbling to life, the Dominantly Inherited Alzheimer’s Network (DIAN) has kicked into gear and is now enrolling research participants at a healthy clip...