Committee Shoots Down Florbetapir, Raising Bar for Field at Large
An FDA Advisory Committee today voted to reject Avid Radiopharmaceutical’s New Drug Application for their amyloid imaging agent AV-45/florbetapir/Amyvid...
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An FDA Advisory Committee today voted to reject Avid Radiopharmaceutical’s New Drug Application for their amyloid imaging agent AV-45/florbetapir/Amyvid...
A new way to measure fibrillar Aβ deposits in the brains of living people has met success in Phase 3 and is poised to ask for regulatory approval...
What does the axonal protein tau have to do with synapses? Quite a bit, some scientists say...
To understand how amyloid plaques, the troublesome clumps of Aβ, form and grow in the brain, it helps to just watch the action directly...
A new strategy for detecting serum antibodies could have important ramifications for Alzheimer’s disease diagnostics...
Epileptic seizures are bad for neurons, but does it come down to zinc ions to finish them off?...
Alzheimer’s disease has seen a disheartening string of failed clinical trials in recent years...
Amber Dance Interviews R. Douglas Fields
New research sustains hopes of boosting cognition through enhancement of the cyclic AMP (cAMP) signaling pathway that turns on memory genes...
In the absence of a definitive test for AD, the diagnosis of dementia remains something of an art, dependent on a clinician’s experience and judgment...
Researchers report stark differences among cognitively normal people enrolled in the Alzheimer’s Disease Neuroimaging Initiative...
Scientists report that there is actually only one future for NG2-positive cells: oligodendrocytes...
The first day of the year is a time for personal reflection...
Years of research have fingered presenilin as the γ-secretase component that slices amyloid precursor protein (APP) to release amyloid-β...
Imaging techniques promise to revolutionize the diagnosis of Alzheimer’s and other neurodegenerative diseases...