Neuroligin 1—A New Substrate for γ-Secretase
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Add another notch in γ-secretase’s belt...
An international group of researchers* have agreed upon recommendations to revise the criteria for postmortem diagnosis of Alzheimer’s disease (AD)...
A new study reports that the ApoE4 gene, previously reported to be over-represented among patients with late onset Alzheimer's disease, appears to be a risk factor only among patients who developed the disease before age 70...
Ibuprofen and related drugs may reduce a person’s risk of getting Alzheimer’s disease by 30 to 60 percent, according to a new study by researchers at Johns Hopkins University and the National Institute on Aging...
An enormous extended family living in a rural community in Colombia could provide new insights into environmental and genetic factors contributing to Alzheimer’s disease. All family members who were diagnosed...
Results released today of a study published in the New England Journal of Medicine indicated that large doses of vitamin E may delay the time at which late-stage Alzheimer's patients must be institutionalized.
Put these two facts together: brain energy metabolism is abnormally low in Alzheimer's patients, and if <a href="http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8710088&form=6&db=m&Dopt=r">your mother had Alzheimer's</a> you are more likely to develop it than if your father had Alzheimer's...
The National Library of Medicine's MEDLINE database is now accessible free to the general public through PubMed and Internet Grateful Med. Hot links to IGM and PubMed are available on the NLM home page...
Researchers in Dr. John Q. Trojanowski's lab at the University of Pennsylvania have discovered a new type of lesion in the brains of Alzheimer's patients...
Researchers at California-based Affymetrix have analyzed the activity of every gene in the yeast genome in a single experiment using a new "DNA chip." This remarkable technological feat hints of a future...
A pathologic form of prion protein is believed to cause scrapie, bovine spongiform encephalopathy and Creutzfeldt-Jakob disease. The normal function of prion protein is yet unknown, but a recent study by Hans Kretzschmar...
Why is the adult mammalian central nervous system unable to regenerate damaged axons? Scarring of glial tissue may be a factor...
An innovative microscope has been developed which provides scientists with a new window through which to explore the dynamics of molecular order and disorder in living cells and other quasi-liquid systems...
Two recent papers describe the processes involved in the final stages of apoptotic cell death. During apoptosis, enzymes known as caspases break down cellular proteins, causing severe morphological changes and cell shrinkage...
Researchers trying to study the role of presenilin-1 (PS1) in Alzheimer's pathogenesis have been stymied by the fact that presenilin knockout mice die before birth...