News Brief: ASG’s Strategic Report, Senate Testimony Freely Available
The Alzheimer's Study Group (ASG) this week released its final report...
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The Alzheimer's Study Group (ASG) this week released its final report...
The deafening buzz of firing neurons can drop to a dull hum if too much Aβ collects in the brain...
Scientists continue to sound out new strategies for re-establishing broken neural connections and for protecting injured spinal cords from further damage...
Sphingolipids, the Sphinx’s modern namesake, may hold clues to the riddle of why some neurons fail to digest Aβ...
Ubiquitin may be everywhere, but when it comes to polyglutamine diseases like Huntington’s (HD), SUMO-1 (small ubiquitin-like modifier 1) may have just as much clout...
Mutations in the presenilin 1 gene (PS1) are responsible for most cases of early-onset familial Alzheimer's disease (FAD). These mutations are accompanied by an increase in β-amyloid peptides.
Amyloid-β precursor protein (AβPP) has gained a notorious reputation because it releases the Aβ peptide that gums up intraneuronal spaces in Alzheimer's brains. Like many of notoriety, however, AβPP probably has a good side...
Both amyloid-β precursor protein (APP) and apolipoprotein E (ApoE) are key players in...
The weird and wonderful world of microbes may hand the field of Alzheimer disease research a physiological function for Aβ...
Last week, neurodegenerative disease researchers from all over the world began a bustling six days of talks, posters, and ample exchange...
The 9th International AD/PD conference, held in Prague 11-15 March, made a big splash in the otherwise sleepy backwater of Alzheimer disease history...
Creutzfeldt-Jakob disease (CJD) is a fatal and transmissible neurodegenerative disease caused by a buildup of misfolded prion proteins in the brain...
What makes prions adopt toxic, self-perpetuating conformations?...
The road to reliable preclinical AD biomarkers has proven long and difficult...
When a patient steps into the doctor’s office and complains of memory problems, it would be nice if a few brain scans could reliably predict the person’s risk of future dementia...