Aβ Oligomers: A Fatal Attraction for Glutamate Receptors?
Clustering around synthetic Aβ oligomers embedded in the cell membrane, metabotropic glutamate receptors unleash an influx of calcium that is toxic to neurons...
6341 RESULTS
Sort By:
Clustering around synthetic Aβ oligomers embedded in the cell membrane, metabotropic glutamate receptors unleash an influx of calcium that is toxic to neurons...
Researchers propose that several-fold increases of α-synuclein can trigger a slew of pathological changes leading to synaptic dysfunction...
Toxic marine algae can cause oceanic dead zones, suffocation in fish, insanity in marine mammals—and perhaps, neurodegenerative disease...
Researchers report that Bcl-2, normally a pro-survival protein, turns bad when it hooks up with SOD1...
Like thermostats that switch on heating or cooling to regulate temperature, neurons tune their excitability up or down to weather environmental changes...
Two new papers highlight the importance in AD of autophagy, a means by which cells dispose of unwanted proteins...
The fight against Alzheimer disease rallies warriors of many sorts...
A study previously featured on Alzforum today appears in the scientific literature...
Four years ago, researchers met in Japan to revise ALS diagnostic criteria with changes that should get people into trials faster...
Researchers have found that motor neurons from people who had died of ALS are likely to have mitochondrial DNA deficiencies and deletions...
Five major pharmaceutical firms are pooling data on 4,000 patients across 11 failed trials into a joint database...
Researchers provide a link between the β amyloid peptide (Aβ) and abnormal fibrin clot formation in cerebral blood vessels...
Three national research agencies issued a joint press release announcing the signing of a cooperation agreement...
In recent years, mounting evidence has pointed to soluble oligomers of Aβ, rather than amyloid fibrils, as the most toxic species in AD...
Deep-brain stimulation looks to become popular for a number of neurological and psychological disorders, even as some of the scientific evidence remains scattered and spotty...