All Comments by Edward Koo

  1. Messing with the Membrane—An Alternative Interpretation of the Amyloid-β Hypothesis
  2. An alternative interpretation of the amyloid Abeta hypothesis with regard to the pathogenesis of Alzheimer's disease.
  3. A scaffold protein JIP-1b enhances amyloid precursor protein phosphorylation by JNK and its association with kinesin light chain 1.
  4. Aβ's Shadowy Sibling—What Becomes of the Intracellular Domain?
  5. Aβ's Shadowy Sibling—What Becomes of the Intracellular Domain?
  6. PEN-2 and APH-1 coordinately regulate proteolytic processing of presenilin 1.
  7. Notch and the amyloid precursor protein are cleaved by similar gamma-secretase(s).
  8. HMG-CoA reductase inhibitors (statins) in the treatment of Alzheimer's disease and why it would be ill-advise to use one that crosses the blood-brain barrier.
  9. FK960, a potential anti-dementia drug, increases synaptic density in the hippocampal CA3 region of aged rats.
  10. A broader horizon of Alzheimer pathogenesis: ALZAS--an early serum biomarker?
  11. Conversion from preclinical to dinical stage of Alzheimer's disease as shown by decline of cognitive function in carriers of the Swedish APP-mutation.
  12. The neurodegeneration mutant löchrig interferes with cholesterol homeostasis and Appl processing.
  13. Vitamin E and C supplements and risk of dementia.
  14. Cyclooxygenase-2 promotes amyloid plaque deposition in a mouse model of Alzheimer's disease neuropathology.
  15. Apolipoprotein E4 influences amyloid deposition but not cell loss after traumatic brain injury in a mouse model of Alzheimer's disease.