All Comments by Edward Koo

  1. Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice.
  2. Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein.
  3. A non-amyloidogenic function of BACE-2 in the secretory pathway.
  4. The amyloidogenic pathway of amyloid precursor protein (APP) is independent of its cleavage by caspases.
  5. Synapse loss is greater in presenile than senile onset Alzheimer disease: implications for the cognitive reserve hypothesis.
  6. High-dose estradiol improves cognition for women with AD: results of a randomized study.
  7. Disturbed activation of endoplasmic reticulum stress transducers by familial Alzheimer's disease-linked presenilin-1 mutations.
  8. Mutant ubiquitin expressed in Alzheimer's disease causes neuronal death.
  9. Amyloid-lowering isocoumarins are not direct inhibitors of gamma-secretase.
  10. Filamentous phage as vector-mediated antibody delivery to the brain.
  11. APP knockout attenuates microglial activation and enhances neuron survival in substantia nigra compacta after axotomy.
  12. The SAMP8 mouse: a model of Alzheimer disease?
  13. Levels of nonphosphorylated and phosphorylated tau in cerebrospinal fluid of Alzheimer's disease patients : an ultrasensitive bienzyme-substrate-recycle enzyme-linked immunosorbent assay.
  14. A case-control analysis of nonsteroidal anti-inflammatory drugs and Alzheimer's disease: are they protective?
  15. Mapping the evolution of regional atrophy in Alzheimer's disease: unbiased analysis of fluid-registered serial MRI.