All Comments by John Hardy

  1. Next-Generation Sequencing: Boldly Going Where No Geneticist...
  2. Genetic signatures of exceptional longevity in humans.
  3. Good Gene, Bad Gene?—New APP Variant May Be Both
  4. SORLA Soars—Large Study Links Gene to Late-onset AD
  5. Haplotype-specific expression of exon 10 at the human MAPT locus.
  6. Highs and Lows: Overactive Synuclein Promoter Linked to Parkinson’s, Tau Loss to Mental Retardation
  7. Birds of a Feather…Mutations in Tau Gene Neighbor Progranulin Cause FTD
  8. Charting Genetic Diversity—First Haplotype Map Appears
  9. Beta amyloid gene duplication in Alzheimer's disease and karyotypically normal Down syndrome.
  10. Alzheimer’s Vaccine: In Some Patients, at Least, It Might Just Work
  11. Substantial linkage disequilibrium across the insulin-degrading enzyme locus but no association with late-onset Alzheimer's disease.
  12. A patient with dementia with Lewy bodies and codon 232 mutation of PRNP.
  13. BSE prions propagate as either variant CJD-like or sporadic CJD-like prion strains in transgenic mice expressing human prion protein.
  14. D90A-SOD1 mediated amyotrophic lateral sclerosis: a single founder for all cases with evidence for a Cis-acting disease modifier in the recessive haplotype.
  15. The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility.