All Comments by Peter Davies
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- Sequential phosphorylation of Tau by glycogen synthase kinase-3beta and protein kinase A at Thr212 and Ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical-filament-like conformation.
- Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice.
- A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Abeta.
- First Alzheimer's diagnosis confirmed.
- The gene defects responsible for familial Alzheimer's disease.
- Apolipoprotein E-containing high density lipoprotein promotes neurite outgrowth and is a ligand for the low density lipoprotein receptor-related protein.
- DNA replication precedes neuronal cell death in Alzheimer's disease.
- Bax protein expression is increased in Alzheimer's brain: correlations with DNA damage, Bcl-2 expression, and brain pathology.
- Transgenic Mice Accumulate Human Tau in Degenerating Hippocampal Neurons
- New Study Correlates Aβ Levels to Degree of Dementia