All Comments by Jürgen Götz
- Calpain Inhibitor A-705253 Mitigates Alzheimer's Disease-Like Pathology and Cognitive Decline in Aged 3xTgAD Mice.
- Neuronal mRNAs travel singly into dendrites.
- Pinning Down Role for Tau Proline Isomers in Alzheimer’s
- Extracting β-amyloid from Alzheimer's disease.
- Atomic identification of fluorescent Q-dots on tau-positive fibrils in 3D-reconstructed pick bodies.
- Using intramolecular disulfide bonds in tau protein to deduce structural features of aggregation-resistant conformations.
- In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice.
- Observations in APP bitransgenic mice suggest that diffuse and compact plaques form via independent processes in Alzheimer's disease.
- Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: a randomized controlled trial.
- Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio.
- The Plot Thickens: The Complicated Relationship of Tau and Aβ
- The Alzheimer's disease mitochondrial cascade hypothesis.
- Caspase activation precedes and leads to tangles.
- Drosophila models of human tauopathies indicate that Tau protein toxicity in vivo is mediated by soluble cytosolic phosphorylated forms of the protein.
- Analysis of microdissected human neurons by a sensitive ELISA reveals a correlation between elevated intracellular concentrations of Abeta42 and Alzheimer's disease neuropathology.