All Comments by David Holtzman
- First Whole-Genome Sequencing of PSP Nets Six New Risk Loci
- The APOE-R136S mutation protects against APOE4-driven Tau pathology, neurodegeneration and neuroinflammation.
- New Therapeutic Strategy—Mimic the ApoE Christchurch Mutation?
- In 3D Cell Model of AD, Microglia and CD8+ T Cells Gang Up on Neurons
- Ridding Microglia of a MicroRNA Compacts Amyloid, Protects Synapses
- Catch and Release: Cryo-EM Reveals How LRP2 Receptor Recycles Cargo
- Healthy, Drug-Resistant Microglia Reinvigorate Mouse Brain
- In AD, CSF Immune Cells Hint at Mounting Mayhem in the Brain
- Meddling Medin: A Vascular Amyloid That Promotes CAA?
- Finally: Big Win on All Outcomes for Lecanemab in Phase 3 Topline Results
- Sans Microglia, Mice Develop CAA and Die Young
- Two ApoE Mutations Decrease Risk for Alzheimer's Disease
- Alzheimer disease neuropathology in a patient previously treated with aducanumab.
- Tau-PET Imaging Brings Braak Staging to Life
- Surprise! TMEM106b Fibrils Found in Neurodegenerative Diseases