All Comments by Paul Coleman

  1. Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau.
  2. Granule cells in aging rats are sexually dimorphic in their response to estradiol.
  3. Transgenic mice overexpressing the neurotrophic factor S-100 beta show neuronal cytoskeletal and behavioral signs of altered aging processes: implications for Alzheimer's disease and Down's syndrome.
  4. Treatment of Alzheimer's disease. New developments.
  5. Prevalence and incidence of clinically diagnosed memory impairments in a geographically defined general population in Sweden. The PiteƄ Dementia Project.
  6. Cyclooxygenase 2 RNA message abundance, stability, and hypervariability in sporadic Alzheimer neocortex.
  7. Neuronal DNA damage precedes tangle formation and is associated with up-regulation of nitrotyrosine in Alzheimer's disease brain.
  8. Overexpression of alpha-internexin causes abnormal neurofilamentous accumulations and motor coordination deficits in transgenic mice.
  9. Apolipoprotein E4, cholinergic integrity and the pharmacogenetics of Alzheimer's disease.
  10. Role of endoplasmic reticulum, endosomal-lysosomal compartments, and microtubules in amyloid precursor protein metabolism of human neurons.
  11. Phosphorylation of tau at both Thr 231 and Ser 262 is required for maximal inhibition of its binding to microtubules.
  12. The order of exposure of tau to signal transduction kinases alters the generation of "AD-like" phosphoepitopes.
  13. Relating anatomy to function in Alzheimer's disease: neuropsychological profiles predict regional neuropathology 5 years later.
  14. Link Between Education Level and AD Risk Strengthened