All Comments by Paul Coleman

  1. Apolipoprotein E4, cholinergic integrity and the pharmacogenetics of Alzheimer's disease.
  2. Role of endoplasmic reticulum, endosomal-lysosomal compartments, and microtubules in amyloid precursor protein metabolism of human neurons.
  3. Phosphorylation of tau at both Thr 231 and Ser 262 is required for maximal inhibition of its binding to microtubules.
  4. The order of exposure of tau to signal transduction kinases alters the generation of "AD-like" phosphoepitopes.
  5. Relating anatomy to function in Alzheimer's disease: neuropsychological profiles predict regional neuropathology 5 years later.
  6. Isoform-specific effect of apolipoprotein E on cell survival and beta-amyloid-induced toxicity in rat hippocampal pyramidal neuronal cultures.
  7. A population-based study on blood pressure and brain atrophy in 85-year-olds.
  8. Visual loss and getting lost in Alzheimer's disease.
  9. Effect of Alzheimer's brain extracts on dynein immunoreactivity in PC12 cells.
  10. Increased glyceraldehyde 3-phosphate dehydrogenase levels in the brain of patients with Down's syndrome.
  11. No hippocampal neuron or synaptic bouton loss in learning-impaired aged beta-amyloid precursor protein-null mice.
  12. Comparison of beta-protein/A4 deposits and Alz-50-stained cytoskeletal changes in the hypothalamus and adjoining areas of Alzheimer's disease patients: amorphic plaques and cytoskeletal changes occur independently.
  13. Hyperactivation of mitogen-activated protein kinase increases phospho-tau immunoreactivity within human neuroblastoma: additive and synergistic influence of alteration of additional kinase activities.
  14. Link Between Education Level and AD Risk Strengthened