All Comments by Hiroshi Mori

  1. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity.
  2. Structural analysis of Alzheimer's beta(1-40) amyloid: protofilament assembly of tubular fibrils.
  3. Sialylated human apolipoprotein E (apoEs) is preferentially associated with neuron-enriched cultures from APOE transgenic mice.
  4. Heparin oligosaccharides that pass the blood-brain barrier inhibit beta-amyloid precursor protein secretion and heparin binding to beta-amyloid peptide.
  5. How to cope with Alzheimer's disease?
  6. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry analysis of proteins in human cerebrospinal fluid.
  7. Effects of specific protease inhibitors on amyloid beta-protein 42 secretion.
  8. Modulation of beta-amyloid precursor protein processing by the low density lipoprotein receptor-related protein (LRP). Evidence that LRP contributes to the pathogenesis of Alzheimer's disease.
  9. Abnormal localization of iron regulatory protein in Alzheimer's disease.
  10. Cellular expression and proteolytic processing of presenilin proteins is developmentally regulated during neuronal differentiation.
  11. Utility of the apolipoprotein E genotype in the diagnosis of Alzheimer's disease. Alzheimer's Disease Centers Consortium on Apolipoprotein E and Alzheimer's Disease.
  12. Increased apolipoprotein E mRNA in the hippocampus in Alzheimer disease and in rats after entorhinal cortex lesioning.
  13. Argyrophilic tau-positive twisted and non-twisted tubules in astrocytic processes in brains of Alzheimer-type dementia: an electron microscopical study.
  14. Down's syndrome is associated with increased 8,12-iso-iPF2alpha-VI levels: evidence for enhanced lipid peroxidation in vivo.
  15. Analysis of message expression in single neurons of Alzheimer's disease brain.