All Comments by Hiroshi Mori

  1. Neuronal DNA damage precedes tangle formation and is associated with up-regulation of nitrotyrosine in Alzheimer's disease brain.
  2. Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins.
  3. Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: central roles of superoxide production and caspase activation.
  4. Alzheimer disease: quantitative H-1 MR spectroscopic imaging of frontoparietal brain.
  5. Apolipoprotein-E deficiency results in an altered stress responsiveness in addition to an impaired spatial memory in young mice.
  6. Cytochrome oxidase in Alzheimer's disease: biochemical, histochemical, and immunohistochemical analyses of the visual and other systems.
  7. Cerebral amyloid angiopathy: amyloid beta accumulates in putative interstitial fluid drainage pathways in Alzheimer's disease.
  8. Alzheimer's amyloid precursor protein alpha-secretase is inhibited by hydroxamic acid-based zinc metalloprotease inhibitors: similarities to the angiotensin converting enzyme secretase.
  9. Intracellular accumulation of detergent-soluble amyloidogenic A beta fragment of Alzheimer's disease precursor protein in the hippocampus of aged transgenic mice.
  10. GM1 ganglioside-bound amyloid beta-protein in Alzheimer's disease brain.
  11. Co-localization of truncated tau and DNA fragmentation in Alzheimer's disease neurones.
  12. Common core structure of amyloid fibrils by synchrotron X-ray diffraction.
  13. Treatment outcome of tacrine therapy depends on apolipoprotein genotype and gender of the subjects with Alzheimer's disease.
  14. Suppression of A beta-induced monocyte neurotoxicity by antiinflammatory compounds.
  15. Association of alpha1-antichymotrypsin polymorphism with cerebral amyloid angiopathy.