All Comments by Hiroshi Mori

  1. Recombinant human amyloid precursor-like protein 2 (APLP2) expressed in the yeast Pichia pastoris can stimulate neurite outgrowth.
  2. Alpha-secretase-derived product of beta-amyloid precursor protein is decreased by presenilin 1 mutations linked to familial Alzheimer's disease.
  3. Specific regional transcription of apolipoprotein E in human brain neurons.
  4. The effects of aging and neurodegeneration on apoptosis-associated DNA fragmentation and the benefits of nicotinamide.
  5. Dementia with Lewy bodies.
  6. Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau.
  7. Glucocorticoids in Alzheimer's disease. The story so far.
  8. Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo.
  9. Amyloid-beta induces chemokine secretion and monocyte migration across a human blood--brain barrier model.
  10. Expression profiles of multiple genes in single neurons of Alzheimer's disease.
  11. Beta-amyloid induces local neurite degeneration in cultured hippocampal neurons: evidence for neuritic apoptosis.
  12. Specific neurochemical derangements of brain projecting neurons in apolipoprotein E-deficient mice.
  13. The beta-amyloid precursor protein of Alzheimer's disease enhances neuron viability and modulates neuronal polarity.
  14. Apoptosis decision cascades and neuronal degeneration in Alzheimer's disease.
  15. Estrogen blocks neurotoxic effects of beta-amyloid (1-42) and induces neurite extension on B103 cells.