All Comments by Sylvain Lesne
- A Minority of Human Aβ Species are Toxic, Good Drug Targets
- End of the EXPEDITION: Solanezumab Results Published
- The CAMKK2-AMPK kinase pathway mediates the synaptotoxic effects of Aβ oligomers through Tau phosphorylation.
- Correlation of Specific Amyloid-β Oligomers With Tau in Cerebrospinal Fluid From Cognitively Normal Older Adults.
- Accuracy of a panel of 5 cerebrospinal fluid biomarkers in the differential diagnosis of patients with dementia and/or parkinsonian disorders.
- Critical role of soluble amyloid-β for early hippocampal hyperactivity in a mouse model of Alzheimer's disease.
- Neurotoxicity and memory deficits induced by soluble low-molecular-weight amyloid-β1-42 oligomers are revealed in vivo by using a novel animal model.
- Seeds of Destruction—Prion-like Transmission of Sporadic AD?
- Bad Guys—Aβ Oligomers Live Up to Reputation in Human Studies
- The Toxic Fold? Aβ Dodecamers, Tetramers Show Their Conformations
- Amyloid beta oligomers (A beta(1-42) globulomer) suppress spontaneous synaptic activity by inhibition of P/Q-type calcium currents.
- San Diego: Oligomers Live Up to Bad Reputation, Part 1
- Aβ Star is Born? Memory Loss in APP Mice Blamed on Oligomer
- New Orleans: Aβ Oligomers and Memory: …Now They Are Bad